Fucidin ointment/ cream

Fucidin ointment –active ingredients Fusidic acid and beclometasone Dipropionate.

Fusidic acid is drug from the bacteriostatic antibiotic group that is frequently applied topically in creams and eye drops, but may also be used under medical observation as tablets or injections. The worldwide difficulty of progressing antimicrobial fight has led to a new attention in its application lately.

Pharmacodynamics

Pharmacokinetics

Fusidic acid (Fucidin ointment) disturbs Trans location of peptide sub units and extending the peptide series of vulnerable bacteria, thus restraining protein production.

Absorption

Fusidic acid is well concerted from the GI tract when used orally; mean plasma absorptions of 30 mcg per ml after 2 to 4 hrs. Speedier metabolism in kids than in adults.

Distribution

widely disseminated into body fluids and tissue as well as pus, bone and synovial fluid; penetrates the placenta and go through breast milk. Protein-binding: 95 percent.

Metabolism

Hepatic; transformed to numerous metabolites.

Excretion

Bile (mainly as metabolites), faeces (2% as unchanged drug), urine; 5-6 hours (elimination half-life).

Fucidin ointment Uses

Treatment of Eczema along with bacterial infection.

Fusidic Acid Adverse Reactions

Fucidin Side Effects

Fusidic acid (Oral) - GI disturbances;liver disorders and Jaundice.

Intravenous: hypocalcaemia; venospasm, haemolysis and thrombophloebitis . SC/IM: cell necrosis.

Topical: skin Rashes, hypersensitivity, irritation and skin pigmentation.

These are not the complete list of Fucidin side effects, for detailed queries consult a doctor.

Precautions

Information Not Available

Special Precautions

• Hepatic disease; Conduct liver test:

• Neonates;

• During pregnancy and lactation.

Other Drug Interactions

Synergistic event when used with anti staphylococcal penicillin. opposition when administered with ciprofloxacin.

Fucidin application

Skin infections

Adult: Fucidin 2% ointment/cream/gel: Use Fucidin Ointment onto the infected region 3 to 4 times every day until there is development. If gauze bandage is recommended, then regularity of use may be decreased to 1 to 2 times every day.

Child: As a 2% ointment/cream/gel: Use Fucidin Ointment onto the infected region 3 to 4 times every day until there is development. If gauze bandage is recommended, then regularity of use may be decreased to 1 to 2 times every day.

Contradictions

• Patients allergic to any of its active ingredients.

• To be used with caution during pregnancy and lactation.