Dicyclomine injection is coming under the category of Anti cholinergic as well as antispasmodic .Its specially given in the case of various types of colic such as intestinal, renal and Biliary specially. Sometimes it’s given in case of the irritable Bowel syndrome, , Dysentery or Acute Diarrhea. Dicyclomine injection are mainly given in Severe and emergency condition.

Mode of Action – Mainly this Dicyclomine take care of the GIT as well as Urinary tract Smooth muscle spasm. It’s mainly due to the antimuscarinic action present by blocking the acetylcholine receptors but yes sometimes it just act directly on the plain Muscle also.

Dosage and Indication – This is always given with the combination of an analgesic but yes for the infants it’s not recommended.

The daily dose should not cross the limit of 80 mg and is given thrice or four times a day in case of adults but yes for children the dose is 10mg thrice a day. Children upon 2 years should not take more than 40 mg of daily dose. The dosage gap should be at least 6 hours.

Route of Administration – Mainly the Dicyclomine injection is given through Intramuscular route especially but yes this could be available as Oral dose tablets, Syrups and capsules forms are also in the market.

Adverse Drug Reaction – If it is used in case of newborn babies less than 10 weeks, there is a chance of respiratory arrest.

In case of adults, excitement, restlessness, confusion may arise. Glaucoma may be accelerate in some cases ,who are having problems in eye.

Tachycardia and urinary retention also been reported in some cases. Patients may also feel tastelessness and feels difficulty in swallowing food. Constipation and dry mouth may occur.

Interaction – Dicyclomine increases the sedative effects of certain anti-anxiety Benzodiazepine class. Antacids may decrease the absorption of Dicyclomine in the body. For this reason, its always recommend that a 2-3 hour gap should be given between this two class.

Safety Measures – The usage of this should be very cautious in some classes of patients like the Elderly as well as infant. It’s also not recommended to give that to the people who are suffering from renal or hepatic disease. Lactating mothers should be avoided to provide this as Dicyclomine may go to the milk and thus affect the infants.

Storage – Stored in room temperature and avoid heat or moisture. Sometimes the injections are stored in Cool condition under refrigeration by maintaining a constant temperature.