PRISTIQ: A Prescription Drug to Treat Major Depressive Disorders in Adults

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Depression and other psychiatric disorders are severe medical conditions that are always linked with increased risk of suicide causing you feel like you need to wind up yourself to get through a day as they really take so much out of you. PRISTIQ, an app

Depression and other psychiatric disorders are severe medical conditions that are always linked with increased risk of suicide. These depressive disorders can really make you feel like you need to wind up yourself to get through a day and they really take so much out of you. Following these disorders, you feel extremely weak, loss of interest, difficulty concentrating, frequent sadness and anxiety and even lack of energy.

What is PRISTIQ?

PRISTIQ belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs) and it is a prescribed drug that contains the medicine desvenlafaxine. PRISTIQ is proven to be effective to treat severe depression in adults and yet, it is not permitted for use in children under 18 and adolescents.

PRISTIQ is considered to perform by affecting the levels of two chemicals found in your brain, namely norepinephrine and serotonin. It is an approved medication that is used in treating major depressive disorders.

What Should I Avoid While Taking PRISTIQ?

You are strictly prohibited from taking this drug while driving, operating machine, doing other dangerous jobs. While taking PRISTIQ, you must also avoid drinking alcohol.

Who Should Not Take PRISTIQ?

Do not take PRISTIQ if you are allergic to venlafaxine, desvenlafaxine or any of the ingredients found in PRISTIQ or are allergic to the use of PRISTIQ, or if you experience allergic reactions after taking PRISTIQ.

Do not take PRISTIQ, if you are currently taking or have taken any drug called an MAOI within the last two weeks (or 14 days). Taking an MAOI with PRISTIQ and also other medications may cause severe or even life-threatening side effects. You must wait at least a week (or 7 days) after you stop taking PRISTIQ before you can take any MAOI.

Prior to Taking PRISTIQ, What Should I Tell My Doctor?

Prior to taking PRISTIQ, please let your doctor or healthcare professional know about all of your medical conditions if you have a history of stroke, lower levels of sodium in your blood, have mania or bipolar disorder, kidney problems, high blood pressure, glaucoma, high triglyceride or cholesterol levels, have or had convulsions or seizure, liver problems, heart problems, have or had bleeding problems.

As with any other drug, PRISTIQ may counteract other medications, so make sure you tell your doctor if you have taken or are taking medications including tryptophan supplements, tramadol, triptans (drugs used to treat migraine headaches), drugs used to treat mood disorders (such as lithium, serotonin norepinephrine reuptake inhibitors-SNRIs, tricyclics, or selective serotonin reuptake inhibitors-SSRIs), MAOIs (including linezolid, an antibiotic), sibutramine or St. John’s Wort. Also, you cannot take PRISTIQ with medications that contain ingredients of desvenlafaxine or venlafaxine. Before you take PRISTIQ with any of these drugs, vitamin pills, supplements, traditional herbals, over-the-counter drugs, as well as other prescribed and non-prescribed drugs, you should talk to your doctor or healthcare provider about serotonin syndrome.

Note: The rare but potentially life-threatening conditions called neuroleptic malignant syndrome (NMS) or serotonin syndrome-like reactions can happen when PRISTIQ is taken with several medications. These syndromes can result in serious changes in how your digestive system, muscles and brain work.

If you are planning to get pregnant or are pregnant, you need to tell your doctor before taking PRISTIQ even though there is no evidence that taking PRISTIQ may harm your unborn baby. You should also let your doctor know if you are breastfeeding or are planning to breastfeed the baby. The reason is that PRISTIQ may pass into your breast milk and there is a concern that it may harm your baby. Also, discuss with your doctor the best alternative to feed your baby if you take or are taking PRISTIQ.

What are the Possible Side Effects of PRISTIQ?

The most common side effects with PRISTIQ include nausea, constipation, anxiety, tiredness, delayed orgasm and ejaculation, dry mouth, tremor, dizziness, sweating, diarrhea, insomnia, sleepiness, decreased sex drive, headache, loss of appetite, dilated pupils and vomiting.

PRISTIQ may cause serious side effects as follow:

  • Increased triglyceride and cholesterol levels in your blood
  • Abnormal bruising or bleeding-Taking PRISTIQ together with other SSRIs/ SNRIs can lead to increased chance of bleeding. Similarly, taking PRISTIQ with blood thinners, aspirin, or non-steroidal anti-inflammatory drugs (NSAIDs) may add to potential risk of bleeding and bruising. Therefore, you are advised your healthcare provider or doctor about any unusual bruising and bleeding you may have encountered while taking this drug immediately.
  • Glaucoma or increased eye pressure
  • May worsen your hypertension (high blood pressure)- Prior to or while taking PRISTIQ, you should have your doctor or healthcare provider monitor your blood pressure. Bear in mind that you should control your blood pressure before start taking PRISTIQ.
  • Low sodium levels in your blood- When the level of sodium is low in your blood, you may experience symptoms include memory changes, unsteadiness on your feet, difficulty concentrating, weakness, confusion, and headache. Under the circumstances of sudden or severe cases, you may also experience coma, fainting, seizure, and hallucinations (meaning you can hear or see things that are not real). If left ignored untreated, lower sodium levels can even cause death.

Other serious side effects of PRISTIQ are neuroleptic malignant syndrome (NMS) or serotonin syndrome-like reactions. You should away get immediate medical assistance when you are encountering with one or more symptoms or signs of these syndromes as follow:

  • Confusion
  • Increased in blood pressure
  • Fast heart beat
  • Muscle stiffness
  • Restlessness
  • Hallucinations (meaning you can hear or see things that are not real)
  • Diarrhea
  • Loss of coordination
  • Nausea
  • Coma
  • Vomiting
  • Increased body temperature

You may also experience symptoms or side effects while discontinuing or stopping PRISTIQ, particularly when you stop the therapy abruptly. Tell your healthcare provider or doctor about these symptoms or side effects, so that they may decrease your dose gradually to help avoid these negative effects. Some of these mentioned effects are sweating, diarrhea, abnormal dreams, insomnia (sleeping problem), dizziness, anxiety, tiredness, headache, nausea, and irritability.

Note: These are only some of the side effects with PRISTIQ, so you should discuss further with your pharmacist, health provider or doctor in regards to all the possible side effects that you will have to experience after taking PRISTIQ. Also, tell your doctor if you have any side effects listed and not listed here or that symptom that hardly goes away two days or more, or PRISTIQ triggers any symptom that may threaten your health.

Final remarks:

Information contained herein is for educational purpose only and does not intend to substitute for any medical treatment, diagnosis or advice. In any medical symptoms or emergency or any acute situation arising from using PRISTIQ, you are advised to consult a registered and qualified doctor immediately for a further diagnosis and advice.

You are encouraged to report any side effects of prescription medications to the FDA by either calling 1-800-FDA-1088 or by visiting

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As always, stay well and healthy!


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