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Ornof (Ofloxacin) Tablets

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Ornof (ofloxacin) tablets Active ingredients: Each coated Ornof tabs contain ornidazole 500 mg and ofloxacin 200 mg. Mechanism of action Ofloxacin is from the group of fluoroquinolone which stops bacterial topoisomerase IV as well as DNA gyrase enzymes

Ornof (ofloxacin) tablets

Active ingredients: Each coated Ornof tabs contain ornidazole 500 mg and ofloxacin 200 mg.

Mechanism of action

Ofloxacin is from the group of fluoroquinolone which stops bacterial topoisomerase IV as well as DNA gyrase enzymes needed for DNA reproduction, repair, transcription and recombination. Ofloxacin works against a broad variety of gram-positive and gram-negative microorganisms.

Absorption: quickly and well absorbed from the Gastro- Intestinal tract (oral); maximum plasma concentrations after 30 minutes – two hours.

Administration

Ornof tabs might be used with or without food. (Keep away from antacids or other drugs with Fe or Zinc within two hours prior to or after administering Ornof ().Please administer plenty of water. )

Contraindications

Allergic reaction to quinolones; pregnancy as well as lactation; persistence of the QT break; unadministered hypokalaemia.

Special Precautions

Epilepsy and/or other inclination to spasms; identified or alleged CNS problems; renal disorders, hepatic impairment; myasthaenia gravis; superinfection; children <18 yr; exposure to strong sunlight and UV light; ensure adequate hydration; elderly.

Ornof side effects

Vomiting, Nausea, diarrhea, abdominal pain; dizziness, headache, hallucinations, insomnia; eosinophilia in addition to leucopenia; dysgeusia; vaginitis; tendon injury and/ or rupture; tremor; anorexia; photosensitivity; allergic reactions. Stop using if neurological, psychiatric, or allergic reactions take place.

Potentially Fatal: infrequently spasms; Anaphylaxis.

These may not be the complete list of possible side effects associated to Ornof (ofloxacin) tablets, consult a doctor for detailed information.

Drug Interactions

Probenecid reduces drug discharge. Antacids may decrease absorption of ofloxacin (ornof tablets), do not use antacids two hour before or after using Ornof tabs. Cimetidine possibly might boost ofloxacin concentrations. Observe blood glucose in subjects on anti diabetic drug administration.

Potentially Fatal: Corticosteroids can amplify danger of tendon rupture. Amplifies actions of ciclosporin, oral anticoagulants, and theophylline. Amplified danger of spasms with NSAIDs. Avoid in subjects administering QT prolonging drugs (e.g. class Ia or III antiarrythmics, terfenadine, astemizole, pentamidine, phenothiazine, cisapride, erythromycin, and a number of TCA).

ATC Classification

J01MA01 - ofloxacin is from the family of fluoroquinolones and is administered for the routine therapy and systemic management of infections.

S01AX11 - ofloxacin is from the family of other anti-infective and is administered for treating eye infections.

‘Ornof (ofloxacin) tablets mayt also be used for other ailments not listed above,

1 comment

PINAKIN THAKRE
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Posted on Dec 16, 2011

About This Article

Niitesh Mundra

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