Liofen- XL (Baclofen)
Baclofen (marketed as Liofen- XL) is an extract of gamma-aminobutyric acid (GABA) principally prescribed for management of spasticity. It is an agonist precise to mammalian other than not (Drosophila) fruit fly GABAB receptors. Its positive actions result from effects at supraspinal and spinal and areas. Liofen- XL (Baclofen) in addition can be taken to take care of hiccups. Studies in rats have demonstrated that the use of Liofen- XL (Baclofen) checks rise in body heat initiated by the preparation MDMA. A very advantageous action of baclofen is that forbearance does not seem to take place to any important quantity in that baclofen keeps hold of its remedial anti-spasmodic actions even after several years of constant use.
Liofen- XL (Baclofen) is an anti-spastic drug. It works by blocking equally polysynaptic as well as monosynaptic reflexes at spinal point.
Liofen- XL (Baclofen) is quickly and properly absorbed from the GI tract following oral administration and it attains top plasma absorptions roughly in about 1 to 3 hours.
Liofen- XL (Baclofen) Side Effects
Sedation, ataxia, sleepiness, giddiness, perplexity (confused state of mind), headache, illusion, skin allergy, enuresis, GI adverse reactions. These adverse reactions are generic and passes away with regular use, consult a specialist in case the problem become importunate and worrying.
Potentially Fatal: CV depression and respiratory problems, convulsions.
In case of any kind of hypersensitivity, stop using it immediately and seek for immediate medical help.
Cerebro-vascular problems, acute psychotic problems, epilepsy, confused state of mind, past account of peptic ulcer, respiratory problems, liver problems, kidney troubles, aged patients, nursing mothers and pregnancy. Don’t stop using the drug abruptly.
Other Drug Interactions
Hypotensive adverse reaction may be amplified when used along with antihypertensive drugs. Parallel administration along with the drug levodopa in subject suffering from Parkinson disease may consequence in agitation, confusion and illusion.
Potentially Fatal: Using Liofen- XL (Baclofen) along with CNS depressants and alcoholic drink can possibly initiate CNS reactions.
Keep the drug in room temperature below 25 degree Celsius. Avoid exposure to direct rays, heat or moisture and keep it safely out of reach of children.