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GTN Sorbitrate CR A Reliable Source of Headache Free Heart Care

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GTN Sorbitrate- CR (2.6 mg and 6.4 mg) is the name of Nitroglycerin controlled release tablets. It is a long-term management drug for treating angina pectoris and heart failure.

What is GTN Sorbitrate- CR?

GTN Sorbitrate- CR (2.6 mg and 6.4 mg) is the name of Nitroglycerin controlled release tablets of Piramal Healthcare Ltd. It is a long-term management drug for treating angina pectoris and heart failure.

What GTN Sorbitrate- CR offers?

It ensures predictable and sustained drug release.

It lessees nitrate headache because of its release pattern.

It provides major reduction of around > 60 % in the severity and frequency of angina.

It provides superior Methocel CR technology.

It prevents instant tablet dissolution.

It Prevents early drug release.

Abridged Prescribing Information:


Every uncoated tablet includes diluted nitroglycerin USP equal to the nitroglycerin 2.6 mg or 6.4 mg (in the controlled release form).


It is used as treatment for angina pectoris.


Here is the list of contra-indications of this drug:

Acute circulatory failure.

Arterial hypoxemia or severe anemia

Associated use with the phosphodiesterase inhibitors like sildenafil.

Cardiogenic shock

Identified hypersensitivity for any part of formation.

Increased intracranial pressure

Pericardial tamponade and constrictive pericarditis

Pronounced hypotension (systolic blood pressure < 90 mm Hg)

Uncorrected hypovolemia

Dosage & Administration:

Dosage should be given according to the necessity and reaction shown by the individual patient as well as severity of angina pain. Suggested dosage is 1 to 2 tablets of 2.6 mg, increased to 13 mg glyceryl trinitrate, managed 2 to 3 times every day.

Elders: Syncope and Hypotension can be a problem with using nitrates in elder people. Children: Data is not accessible of efficacy and safety

Warning & Precautions:

Keep away from reach of children.

Caution advised while this medicine is used in:

Ambulant patients having combination of valvular aortic stenosis (moderate to severe) and angina.

Core pulmonary or lung disease

During drug withdrawn

Early stages of acute myocardial infraction

Issues, which have volume reduction from diuretic therapy otherwise, who have lower systolic BP.

Ruthless ischemic heart disease


Exasperation of angina resulted by methemoglobinemia and hypertrophic cardiomyopathy reported.

Pregnancy/ Lactation:

In pregnancy/lactation, physician’s caution is advised.

Drug Interaction:

Caution is advised in case this drug is co-administered through agents, which directly or indirectly effects on the calcium channel blockers, vascular smooth muscle, alcohol, sildenafil, long acting nitrates, and try cyclic antidepressants.

Adverse Effects:

Usually reported adverse effects consist of headache, facial flushing, light-headedness, dizziness, tachycardia, halitosis, fainting, syncope, hypotension, palpitations, exfoliactive dermatitis, rarely bradycardia and reduced arterial oxygen tension.

Dose can be restricted due to vascular headaches. Large doses can result into vomiting, apprehension, cynosis, methemoglobinemia, restlessness, impairment respiration and drug rash.


It comes in bottle pack of 30 tablets (both 2.6 mg as well as 6.4 mg)


Store in a dark, cool, and dry place

Replace the cap firmly after use

Discard the remaining tablets after 8 weeks after opening its pack

Photo Credit: Sideshowmon at morguefile [.] com


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Dharmesh Tolia

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