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Duphalac Syrup (Lactulose)

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Duphalac syrup (Lactulose) Lactulose is a artificial sugar used in the management of hepatic encephalopathy and constipation, a impediment of liver infection. The profit-making syrup used for management of constipation is tinted yellowish orange. It is

 Duphalac syrup (Lactulose)

Lactulose is a artificial sugar used in the management of hepatic encephalopathy and constipation, a impediment of liver infection. The profit-making syrup used for management of constipation is tinted yellowish orange. It is produced and marketed for business by isomerization of lactose.

Pharmacokinetics

Duphalac syrup (Lactulose) encourages peristalsis by generating an osmotic consequence in the colon with consequential distention. In case of hepatic encephalopathy, it decreases assimilation of noxious nitrogenous compounds and ammonium ions, ensuing in condensed blood ammonia absorptions.

Lactulose Adverse Reactions

Duphalac syrup Side Effects

Diarrhea (as per dose), vomiting, nausea, hypokalaemia, abdominal cramps and bloating. Stop using the medication and consult a doctor immediately in case any of these side effects become persistent and bothersome.

Potentially Fatal: hypernatraemia and dehydration on insistent therapy.

These may not be the whole list of possible side effects of Duphalac syrup, for full details consult a nearby doctor.

Precautions

Since Duphalac syrup (Lactulose) is made up of lactose (< 1.6 gm per 15 milliliter) and galactose (< 1.2 gm per 15 milliliter), it must be administered with carefulness in patients suffering from diabetics.

Special Precautions

Observe electrolyte disparity. Lactose bigotry; patients suffering from diabetes.

Other Drug Interactions

May stop discharge of mesalazine in the colon. Reduced effectiveness with antacids and oral neomycin.

Other Interactions

Information Not Available

Food (before/after)

Duphalac syrup (Lactulose) May be administered with or with no food. Suggested to take with meal to keep away from GI disorders.

List of Contraindications

Lactulose and Pregnancy

Category B: Either animal reproduction tests have not verified a fetal danger but there are no confirmed tests in case of pregnancy or animal reproduction tests have demonstrated an undesirable result (other than a dwindle in productiveness) that was not established in controlled researches in women in the first trimester (and there is no proof of a threat in later trimesters).

Lactulose and Lactation

No results known.

Lactulose and Children

Safety and efficiency not recognized. Use with caution. Newborn using Duphalac syrup (Lactulose) may be exposed to the risk of dehydration and hyponatremia.

Lactulose and Geriatic

With long-term treatment (> 6 mnths) at augmented danger of lack of fluids and electrolyte disparity.

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Niitesh Mundra

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