Appetite Stimulant Facts

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Buclizine, lysine, pizotifen and dibencozide are common appetite enhancers. Here are some info, precautions, side-effects, drug interactions and the common brand names.

While some people perform strenuous exercises or take diet pills to lose weight, there are also individuals who would want to gain extra pounds. Athletes for instance, would want more muscles and to do that they must take a lot of protein enriched foods. Parents would want their kids to eat more to be healthy. Eating disorders, like anorexia is another reason. Eating disorders result in immense weight loss and can result to death from the lack of nutrition.

Experts recommend more calorie intake to gain weight. However, motivating someone to eat can be tough as losing weight.

The following are facts about some appetite enhancers usually prescribed by physicians.

  • Buclizine

Buclizine hydrochloride is actually an antihistamine. It is of synthetic origin, belonging to Piperazine. Buclizine is mainly used for anti-emetic action, particularly in prevention of motion sickness, also used in combination with analgesics to treat migraine attacks. As an appetite stimulant, it is compared to cyproheptadine- an appetite stimulant banned in UK.

Unlike cyproheptadine, buclizine increases both appetite and absorption of food in the body. It doesn’t affect the growth hormone levels. Cyproheptadine increases appetite by inhibiting growth hormone. Therefore, cyproheptadine is not good for the growth in children. More to this, buclizine is better than cyproheptadine because it can maintain weight gain even after the discontinuation of treatment.

As a single product, a common brand name of buclizine is Longifene. The drug is categorized as an antihistamine and anti-allergy class with the 25mg tab and 6mg 200ml liquid strength and dosage form respectively.

Buclizine in combination with other vitamins has the following popular trade names: Appebon 500 (tab with 25mg buclizine and 5mg in syrup), Appebon with iron (tablet or capsule with 25 buclizine and 5mg in syrup), Nervostamin (capsule with 25mg buclizine), Propan with iron (capsule with 25mg buclizine) and Regeron-E plus (capsule with 25mg buclizine).

Buclizine precautions: Renal and hepatic impairment, pregnancy, open-angle glaucoma, urinary retention, prostatic hyperplasia, pyloroduodenal obstruction and epilepsy.

Buclizine side effects: Fatigue, nausea drowsiness, diarrhea, palpitation, constipation, insomnia, dry mouth, depression, tremor, nightmares, gastric pain, urinary retention and dry mouth.

Buclizine drug interactions: Alcohol, sedatives, CNS depressants.

  • Lysine

Lysine is normally found in a multivitamins preparation and can also be found in combination with buclizine. Lysine is an essential amino acid. It is not directly an appetite stimulant like pizotifen and buclizine, but because it helps in the production of enzymes which aid in digestion, lysine can also act as an appetite enhancer.

Some brands with lysine in combination with other vitamins are the following: Celermin, Chlorvytol, Crescin, Enouvim, Esvimin, Growee, Incremin, Kiddie Pharmaton, Macrobee with lysine, Medgivit, Molvite with Iron, Nutroplex etc.

With buclizine, appetite motivation can be enhanced more. Here are the trade names of lysine with buclizine:

Appebon 500 syrup, Appebon with iron syrup and Nervostamin capsule or syrup.

Lysine precautions: Renal impairment, pregnant and lactating mothers, patients with hypercholesterolemia.

Lysine side effects: Serious symptoms include swelling of face, lips and tongue, difficulty in breathing and closing of throat. Excessive consumption of lysine supplements have also shown considerable increase in bad cholesterol levels and have also caused gallstones, stomach cramps and diarrhea.

Lysine drug interactions: Antibiotics like gentamicin, tobramycin, amikacin, kanamycin, netilmicin, neomycin, streptomycin and tobramycin.

  • Pizotifen

Pizotifen is benzocycloheptane based drug used primarily for the prevention or to reduce the frequency of migraine headaches. Besides being an appetite stimulant, pizotifen is also classified as a psychotherapeutic drug. It is usually indicated for anorexia and depressive mood in the elderly.

Available products as a single form: Litec, Mosegor, Drugmaker’s Biotech Pizotifen.

Available products in combination with other vitamins: Appetens and Mosegor Vita.

Pizotifen precautions: Narrow angle glaucoma, urinary retention, pregnancy and lactation.

Pizotifen side effects: Dizziness, dry mouth and constipation.

Drug interactions: Alcohol, sedatives, hypnotics, antihistamines.

  • Dibencozide

Dibencozide also known as cobalamin enzyme or adenosylcobalamin is the most active type of vitamin B12. Not only that it is important for producing new blood cells, dibencozide is also an effective appetite enhancer.

Dibencozide is usually indicated for premature babies and infants with low birth weight; for children and adults with poor appetite; and for those people who are recovering from critical cases such as strokes and depression. It increases protein, carbohydrate and fat metabolism, which indirectly stimulates appetite. More to this, dibencozide can also improve mental concentration, muscle mass and strength.

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Heraclene, Aktibol, Bidicozan, Biotrefon- L, Calomide, Cobaxid and Cobazim are popular brand names of dibencozide.

Dibencozide precautions: Pregnancy and breast-feeding; gastrointestinal conditions such as ileal disease for this can reduce that amount of Vitamin B12, including dibencozide, which is absorbed from the intestine.

Dibencozide side effects: No reported side effects.

Dibencozide drug interactions: Chloramphenicol. Taking chloramphenicol for a long time might decrease the effects of dibencozide on new blood cells.


This article is solely for info. Seeking medical advice from a registered physician is still the best.

© Phoenix Montoya @ January 13, 2011


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